The Arizona Wildcats look to end their losing streak in season openers when they visit the San Diego State Aztecs on Saturday in the first game of the 2022 season for both teams. Arizona has lost four consecutive openers since routing Northern Arizona 62-24 in 2017. The Wildcats are coming off a 1-11 campaign and have lost 23 of their last 24 overall contests. San Diego State set a school record last year with 12 victories, including a 38-14 triumph at Arizona.

Kickoff at Snapdragon Stadium is set for 3:30 p.m. ET. The Aztecs are 6-point favorites in the latest San Diego State vs. Arizona odds from Caesars Sportsbook, while the over/under for total points scored is 46.5. Saturday’s game can be seen live on CBS and streamed live on Paramount+ with their must-have Premium plan.

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How to watch San Diego State vs. Arizona

  • San Diego State vs. Arizona date: Saturday, September 3 
  • San Diego State vs. Arizona time: 3:30 p.m. ET 
  • San Diego State vs. Arizona TV: CBS 
  • San Diego State vs. Arizona live stream: Paramount+

Before making any Arizona vs. San Diego State picks, you need to see the college football predictions and betting advice from the SportsLine Projection Model.

The model simulates every FBS college football game 10,000 times. Over the past six-plus years, the proprietary computer model has generated a stunning profit of almost $3,600 for $100 players on its top-rated college football picks against the spread. It enters Week 1 of the 2022 college football season on a 45-32 run on all top-rated college football spread and money-line picks that dates back to 2021. Anyone who has followed it has seen huge returns.

Now, the model has set its sights on San Diego State vs. Arizona and just locked in its picks and CFB predictions. You can visit SportsLine now to see the model’s picks. Here are the college football odds and betting lines for Arizona vs. San Diego State: 

  • San Diego State vs. Arizona spread: Aztecs -6 
  • San Diego State vs. Arizona over/under: 46.5 points 
  • San Diego State vs. Arizona money line: Aztecs -240, Wildcats +196 
  • SDSU: The Aztecs are 11-5 against the spread in their last 16 home games 
  • AZ: The Wildcats are 8-24 ATS in their last 32 road contests 
  • San Diego State vs. Arizona picks: See picks here.

Featured Game | San Diego State Aztecs vs. Arizona Wildcats

Why San Diego State can cover

The Aztecs boasted a stellar defense last season, ranking 12th in the nation in total defense (324.4 yards) and 17th in scoring defense (19.8 points). San Diego State’s secondary played a huge role in the team’s success as it was tied for fifth in the country with 17 interceptions, most in the Mountain West. Senior safety Patrick McMorris earned first-team all-conference honors after leading the Aztecs with four picks.

San Diego State’s offense will be led by quarterback Braxton Burmeister, who won the starting job after transferring from Virginia Tech. Last season, Burmeister threw for 1,960 yards and 14 touchdowns with only four interceptions in 12 games with the Hokies. He’ll be hoping to form a strong connection with wide receiver Jesse Matthews, who led San Diego State in 2021 with 57 receptions, 642 yards and nine TD catches — the most by an Aztec since Vincent Brown had 10 in 2010.

Why Arizona can cover

The Wildcats have had the upper hand in the all-time series against San Diego State, winning 10 of their 16 meetings — including four straight prior to last year’s defeat. Arizona was victorious in its last two road contests versus the Aztecs, recording a 35-16 win in 1998 and a 23-10 triumph three years later. The Wildcats are hoping an aerial attack led by the new duo of quarterback Jayden de Laura and wide receiver Jacob Cowing can help lead them to another road victory in the series.

A transfer from Washington State, de Laura was the 2021 Pac-12 Offensive Freshman Player of the Year after recording 2,798 passing yards and 23 touchdowns with the Cougars. The native of Hawaii also ran for three scores, one more than Arizona’s signal-callers registered last season. Cowing, who spent the last three years at UTEP, was ninth in the nation with 1,354 receiving yards in 2021 and also hauled in a career-high seven TD passes.

How to make San Diego State vs. Arizona picks

SportsLine’s model is leaning Over on the point total, projecting the teams combine for 50 points. It also has generated an against-the-spread pick that cashes in well over 70% of simulations. You can only get the model’s pick at SportsLine.

So who wins Arizona vs. San Diego State? And which side of the spread hits well over 70% of the time? Visit SportsLine now to see which side of the San Diego State vs. Arizona spread to back, all from the advanced model that is up almost $3,600 on its top-rated college football spread picks, and find out.



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